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PNU-282987 free base - CAS 711085-63-1
PNU-282987 free base - CAS 711085-63-1
SKU:MF-0097560-01
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$32.42 USD
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$32.42 USD
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Product Details
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Bioactivity
PNU-282987 (free base) is a potent agonist of α7 nicotinic acetylcholine receptor (nAChR) with an EC50 of 154 nM and a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. It can be used for central and peripheral nervous system studies[1].
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Target
5-HT Receptor, AChR
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Related Pathways
GPCR/G Protein, Neuroscience
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CAS Number
711021
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Purity
0.9964
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Molecular Formula
C14H17ClN2O
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Molecular Weight
264.75
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SMILES
Clc1ccc(cc1)C(=O)N[C@H]1CN2CCC1CC2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound