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Molfinity

PNU-282987 free base - CAS 711085-63-1

PNU-282987 free base - CAS 711085-63-1

SKU:MF-0097560-01

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  • Bioactivity

    PNU-282987 (free base) is a potent agonist of α7 nicotinic acetylcholine receptor (nAChR) with an EC50 of 154 nM and a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. It can be used for central and peripheral nervous system studies[1].

  • Target

    5-HT Receptor, AChR

  • Related Pathways

    GPCR/G Protein, Neuroscience

  • CAS Number

    711021

  • Purity

    0.9964

  • Molecular Formula

    C14H17ClN2O

  • Molecular Weight

    264.75

  • SMILES

    Clc1ccc(cc1)C(=O)N[C@H]1CN2CCC1CC2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound