Molfinity

PNU-74654 - CAS 113906-27-7

SKU:MF-0014966-01

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Size 2 mg 5 mg 1 mL - 10 mM (in DMSO) 10 mg 25 mg 50 mg 100 mg 200 mg

Product Details

Bioactivity
PNU 74654 binds to β-catenin (Kd = 450 nM), inhibiting its interaction with the transcription factor T cell factor 4 (Tcf4) resulting in disruption of the Wnt signaling pathway.
Target
Apoptosis, Wnt/beta-catenin
Related Pathways
Stem Cells, Apoptosis, Cytoskeletal Signaling
CAS Number
113872
Purity
0.98
Molecular Formula
C19H16N2O3
Molecular Weight
320.34
SMILES
Cc1ccc(\C=N\NC(=O)c2ccccc2Oc2ccccc2)o1
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound