PNZ5 - CAS 1629277-36-6

PNZ5, an isoxazole-based pan-BET inhibitor, demonstrates potent activity and high selectivity comparable to the established (+) -JQ1, exhibiting a dissociation constant (KD) of 5.43 nM for BRD4 (1) .

Epigenetic Reader Domain

Chromatin/Epigenetic

1629235

>99.99%

C20H18N2O2

318.37

CN1[C@H](C=2C(C1=O)=CC=C(C2)C=3C(C)=NOC3C)C4=CC=CC=C4

-20°C

Ice Packs

Small Compound