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Polθ-IN-3 - CAS 2922287-81-6

Polθ-IN-3 - CAS 2922287-81-6

SKU:MF-0121740-01

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  • Bioactivity

    Polθ-IN-3 (Compound 113), an orally active Polymerase Theta (Polθ) inhibitor, exhibits antitumor activity.

  • Target

    DNA/RNA Synthesis

  • Related Pathways

    DNA Damage/DNA Repair, Cell Cycle/Checkpoint

  • CAS Number

    2922287-81-6

  • Molecular Formula

    C24H19F2N7O2S

  • Molecular Weight

    507.52

  • SMILES

    O=C(NC1=NN=C(C#CC2CC2)S1)C=3C=NC(=CC3C4=CC(=NC=C4OC)C(F)F)C5=NN(C=C5)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound