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Molfinity

Polθ-IN-7 - CAS 2923356-52-7

Polθ-IN-7 - CAS 2923356-52-7

MF-0112726-01

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Product Details

  • Bioactivity

    Polθ-IN-7 (example 12) is an inhibitor of DNA polymerase θ (Polθ) with a Ki of 1.27 nM.

  • Target

    DNA/RNA Synthesis

  • Related Pathways

    DNA Damage/DNA Repair, Cell Cycle/Checkpoint

  • CAS Number

    2923297

  • Molecular Formula

    C28H35F3N6O2

  • Molecular Weight

    544.612

  • SMILES

    O=C1[C@]2(N(C(=O)C[C@@]2(CN(CCN3CCN(C)CC3)C=4C(N1C)=CC=CC4C)[H])C5=CC(C(F)(F)F)=CC(C)=N5)[H]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound