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Molfinity

Polθ-IN-8 - CAS 3056743-98-4

Polθ-IN-8 - CAS 3056743-98-4

MF-0115537-01

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Product Details

  • Bioactivity

    Polθ-IN-8 (example 77) is a DNA polymerase θ (Polθ) inhibitor with an IC50 for Polθ ATPase activity of less than 100 nM. Polθ-IN-8 is useful for researching diseases related to Polθ activity, such as cancer.

  • Target

    DNA/RNA Synthesis

  • Related Pathways

    DNA Damage/DNA Repair, Cell Cycle/Checkpoint

  • CAS Number

    3056641

  • Molecular Formula

    C22H22ClN7O3S

  • Molecular Weight

    499.97

  • SMILES

    O=C(NC1=NC=2C=NC(=NC2S1)NCC(O)(C)C)C=3C=NC(=CC3C4=CC(Cl)=NC=C4OC)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound