Poloxipan - CAS 1239513-63-3

Poloxipan is a potent and pan-specific PLK1 inhibitor. In vitro, Poloxipan has IC50 3.2 uM (Plk1) ; 1.7 uM (Plk2) ; and 3 uM (Plk3) . Poloxipan showed minor inhibition over FHA dommain of Chk2, S2 domian of STAT1, STAT5b, Lck, etc.

Others, PLK, STAT

Others, Cell Cycle/Checkpoint, JAK/STAT signaling, Stem Cells

1239447

C14H10BrN3O3S

380.22

O=C\1N2C(S/C1=C\C3=C(OC)C=CC(Br)=C3)=NC(=O)C(C)=N2

-20°C

Ice Packs

Small Compound