PolQi1 - CAS 2607139-80-8

PolQi1 is a highly efficient and selective PolΘ (DNA polymerase theta) inhibitor with an IC50 of 2 nM, showing potential for cancer therapy.

DNA/RNA Synthesis

DNA Damage/DNA Repair, Cell Cycle/Checkpoint

2607139-80-8

0.9897

C18H14ClF5N4O2

448.77

C(N(C)C1=C(F)C(Cl)=C(F)C=C1)(=O)[C@H]2N(C(=O)NC2)C3=CC(C(F)(F)F)=CC(C)=N3

-20°C

Ice Packs

Small Compound