Polycarpine hydrochloride - CAS 175669-29-1

Polycarpine hydrochloride (1a), a broad-spectrum Mpro inhibitor (IC 50 = 30 nM), is sourced from Polycarpa aurata and functions as an anti-coronaviral agent. This compound exhibits both antiviral and antifungal properties, with IC 50 values of 30.0 nM against SARS-CoV-2 Mpro and 0.12 μM against PEDV Mpro [1].

Influenza Virus, SARS-CoV, Antifungal, Virus Protease

Microbiology/Virology

175669-29-1

C22H26Cl2N6O2S2

541.52

S(SC1=C(N=C(N)N1C)C2=CC=C(OC)C=C2)C3=C(N=C(N)N3C)C4=CC=C(OC)C=C4.Cl.Cl

-20°C

Ice Packs

Natural Product