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Molfinity

Polygalacic acid - CAS 22338-71-2

Polygalacic acid - CAS 22338-71-2

SKU:MF-0096731-01

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  • Bioactivity

    Polygalacic acid (Virgaureagenin G) is a triterpenoid isolated from the root of Polygala tenuifolia Willd that inhibits MMP expression. Polygalacic acid (Virgaureagenin G) can significantly improve the responsiveness of the cholinergic system, such as decreased acetylcholinesterase (AChE) activity, increased choline acetyltransferase (ChAT) activity, and increased acetylcholine (ACh) levels in the hippocampus and frontal cortex. Polygalacic acid (Virgaureagenin G) can also inhibit IL-1β-induced Wnt/β-catenin activation and mitogen-activated protein kinase (MAPK) signaling pathways in chondrocytes, and is used in osteoarthritis (OA) related research.

  • Target

    AChR, MMP, Cholinesterase (ChE)

  • Related Pathways

    Neuroscience, Proteases/Proteasome

  • CAS Number

    22265

  • Purity

    0.9982

  • Molecular Formula

    C30H48O6

  • Molecular Weight

    504.7

  • SMILES

    CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@H](O)[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@H]2C1)C(O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product