Molfinity
Polygalacic acid - CAS 22338-71-2
Polygalacic acid - CAS 22338-71-2
SKU:MF-0096731-01
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Product Details
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Bioactivity
Polygalacic acid (Virgaureagenin G) is a triterpenoid isolated from the root of Polygala tenuifolia Willd that inhibits MMP expression. Polygalacic acid (Virgaureagenin G) can significantly improve the responsiveness of the cholinergic system, such as decreased acetylcholinesterase (AChE) activity, increased choline acetyltransferase (ChAT) activity, and increased acetylcholine (ACh) levels in the hippocampus and frontal cortex. Polygalacic acid (Virgaureagenin G) can also inhibit IL-1β-induced Wnt/β-catenin activation and mitogen-activated protein kinase (MAPK) signaling pathways in chondrocytes, and is used in osteoarthritis (OA) related research.
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Target
AChR, MMP, Cholinesterase (ChE)
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Related Pathways
Neuroscience, Proteases/Proteasome
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CAS Number
22265
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Purity
0.9982
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Molecular Formula
C30H48O6
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Molecular Weight
504.7
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SMILES
CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@H](O)[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@H]2C1)C(O)=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product