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Polyinosinic-polycytidylic acid potassium - CAS 31852-29-6
Polyinosinic-polycytidylic acid potassium - CAS 31852-29-6
SKU:MF-0154529-01
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Product Details
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Bioactivity
Polyinosinic-polycytidylic acid potassium (Poly (I:C) potassium), a synthetic double-stranded RNA analog, serves as an agonist for toll-like receptor 3 (TLR3) and retinoic acid-inducible gene I (RIG-I) -like receptors (RIG-I and MDA5), offering applications in immunotherapy. Its sodium variant enhances both innate and adaptive immune responses when used as a vaccine adjuvant and is instrumental in modifying the tumor microenvironment. Additionally, Poly (I:C) potassium can directly induce apoptosis in cancer cells [1] [2] [3].
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Target
TLR, Others, Apoptosis
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Related Pathways
Immunology/Inflammation, Apoptosis, Others
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CAS Number
31817
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Molecular Formula
(C10H13N4O8P) x. (C9H14N3O8P) x.xK
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound