Polyphemusin I - CAS 125139-67-5

Polyphemusin I, an amphiphilic antiparallel β-hairpin peptide stabilized by two disulfide bridges, comprises 18 amino acids and exhibits potent antimicrobial activity against both Gram-negative and Gram-positive bacteria [1].

Antibacterial

Microbiology/Virology

125067

C108H161N39O20S4

2453.94

C([C@@H](C(N[C@@H]1C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@]3(C(=O)N[C@@H](CC4=CC=C(O)C=C4)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CC5=CC=CC=C5)C(=O)N[C@@](CSSC3)(C(=O)N[C@@H](CC6=CC=C(O)C=C6)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CSSC1)[H])[H])=O)NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCCNC(=N)N)=O)C=7C=8C(NC7)=CC=CC8

-20°C

Ice Packs

Peptide