Pomalidomide-amido-C1-Br - CAS 2351106-38-0

Pomalidomide-amido-C1-Br is a synthesized conjugate consisting of the Pomalidomide-based cereblon ligand and a linker, functioning as an E3 ligase ligand-linker. This compound serves as a tool for designing a B-Raf PROTAC degrader, specifically PROTAC B-Raf degrader 1, which exhibits anti-cancer activity[1].

Others, E3 Ligase Ligand-Linker Conjugate

PROTAC, Others

2351068

C15H12BrN3O5

394.18

O=C(NC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3)CBr

-20°C

Ice Packs

PROTAC