Ponicidin - CAS 52617-37-5

Ponicidin (Rubescensine B) is a diterpenoid derived from Rabdosia rubescens that exhibits immunoregulatory, anti-inflammatory, anti-viral, and anti-cancer activity. Ponicidin induces apoptosis of gastric carcinoma cells, decreases the phosphorylation of JAK2 and STAT3, and shows no effect on the protein levels of JAK2 and STAT3.

JAK, STAT, Apoptosis

Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Stem Cells, Apoptosis, Angiogenesis, JAK/STAT signaling

52575

0.9992

C20H26O6

362.42

[H][C@]12CC[C@]3([H])[C@]4(C(=O)C1=C)[C@@]2([H])O[C@@]1([H])O[C@]4(O)[C@@H](O)[C@]2([H])C(C)(C)CC[C@H](O)C312

-20°C

Ice Packs

Natural Product