Molfinity

Poziotinib - CAS 1092364-38-9

SKU:MF-0013057-01

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Size 1 mg 5 mg 1 mL - 10 mM (in DMSO) 10 mg 25 mg 50 mg 100 mg

Product Details

Bioactivity
Poziotinib (NOV120101) (NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM) .
Target
Apoptosis, EGFR, HER
Related Pathways
JAK/STAT signaling, Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors
CAS Number
1092317
Purity
0.9978
Molecular Formula
C23H21Cl2FN4O3
Molecular Weight
491.34
SMILES
COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1OC1CCN(CC1)C(=O)C=C
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound