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Poziotinib hydrochloride - CAS 1429757-68-5

Poziotinib hydrochloride - CAS 1429757-68-5

MF-0013625-01

$32.42 USD
$32.42 USD
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Product Details

  • Bioactivity

    Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. It is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.

  • Target

    EGFR

  • Related Pathways

    Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors

  • CAS Number

    1429684

  • Purity

    0.9981

  • Molecular Formula

    C23H22Cl3FN4O3

  • Molecular Weight

    527.8

  • SMILES

    Cl.COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1OC1CCN(CC1)C(=O)C=C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound