PP121 - CAS 1092788-83-4

PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (IC50: 10 nM), VEGFR2 (IC50: 12 nM), Src (IC50: 14 nM) and Abl (IC50: 18 nM), also inhibits DNA-PK (IC50: 60 nM) .

PDGFR, VEGFR, Apoptosis, mTOR, Hck, Src, Bcr-Abl

Apoptosis, PI3K/Akt/mTOR signaling, Angiogenesis, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors

1092701

0.9993

C17H17N7

319.36

Nc1ncnc2n(nc(-c3cnc4[nH]ccc4c3)c12)C1CCCC1

-20°C

Ice Packs

Small Compound