PPA-037 - CAS 2883700-83-0

PPA-037 is an orally active and highly selective inhibitor of cyclin-dependent kinase 12 (CDK12) . It induces the degradation of Cyclin K, thereby enhancing antiproliferative effects on tumor cells. PPA-037 holds potential for use in cancer research.

CDK

Cell Cycle/Checkpoint

2883617

C25H27N7

425.53

N(CC1=CC=C(C=C1)C2=CC=CC=N2)C=3N4C(=C(C=N4)C5CC5)N=C(N[C@H]6CCNC6)C3

-20°C

Ice Packs

Small Compound