PPARα/δ agonist 1 - CAS 2760128-48-9

PPARα/δ agonist 1 is a potent dual agonist with EC50 values of 7.0 nM for PPARα and 8.4 nM for PPARδ, exhibiting high selectivity for PPARγ (EC50: 1316.1 nM) . Agonist 1 has potential for non-alcoholic steatohepatitis studies.

Others, PPAR

Others, Metabolism, DNA Damage/DNA Repair

2760071

C22H22F3N3O5

465.42

O=C1N(C=NN1CC2=CC(C)=C(OC(C(O)=O)(C)C)C(C)=C2)C3=CC=C(OC(F)(F)F)C=C3

-20°C

Ice Packs

Small Compound