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PPARγ agonist 16 - CAS 2218046-01-4
PPARγ agonist 16 - CAS 2218046-01-4
SKU:MF-0112449-01
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Product Details
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Bioactivity
PPARγ agonist16 (Compound 4G) is a PPARγ agonist that competitively binds to the ligand-binding domain (LBD) of PPARγ with an IC50 of 1790 nM. It reduces ear swelling in mouse models and exhibits antihyperglycemic activity in mice with Streptozotocin-induced diabetes.
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Target
PPAR
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Related Pathways
Metabolism, DNA Damage/DNA Repair
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CAS Number
2218046-01-4
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Molecular Formula
C19H14BrNO4S
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Molecular Weight
432.29
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SMILES
O=C1SC(=CC=2C=CC=CC2OC)C(=O)N1CC(=O)C3=CC=C(Br)C=C3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound