PPARγ agonist 17 - CAS 3054652-58-0

PPARγ agonist17 (Compound C1) is an orally active PPARγ agonist. It enhances PPARγ activity, arrests the cell cycle of HT-29 cells at the G2/M phase, inhibits cell migration, and induces apoptosis. PPARγ agonist17 exhibits broad-spectrum antiproliferative activity against cancer cells with relatively low toxicity to normal cells and does not cross the blood-brain barrier.

PPAR

DNA Damage/DNA Repair, Metabolism

3054594

C48H63NO7

766.016

C[C@]12[C@@]3(C)C([C@]4([C@@](C)(CC3)CC[C@@](C(O)=O)(C)C4)[H])=CC(=O)[C@@]1([C@]5(C)[C@@](CC2)(C(C)(C)[C@@H](OC(CC6=CC(NC(COC7=C(C)C=CC(C)=C7)=O)=CC=C6)=O)CC5)[H])[H]

-20°C

Ice Packs

Small Compound