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PPARδ agonist 9 - CAS 928023-21-6

PPARδ agonist 9 - CAS 928023-21-6

MF-0156858-01

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Product Details

  • Bioactivity

    PPARδ agonist 9 (compound 21), with an EC50 of 3.6 nM, effectively decreases serum MCP-1 concentrations in mice and significantly reduces atherosclerotic development in the LDLr-KO model with a 50-60% inhibition rate in vivo [1].

  • Target

    PPAR

  • Related Pathways

    DNA Damage/DNA Repair, Metabolism

  • CAS Number

    927996

  • Molecular Formula

    C26H28ClF3N4O3S

  • Molecular Weight

    569.04

  • SMILES

    C(COC1=CC(CC(O)=O)=CC(Cl)=C1)C2(CCN(CC2)C=3SC=4C(N3)=CC=C(C(F)(F)F)N4)N5CCCC5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound