PPL agonist-1 - CAS 3040997-52-9

PPL agonist-1 (Compound I-3) is a highly selective agonist of Periplakin (PPL) that raises cAMP levels by modulating PPL, enhancing MITF expression, and consequently promoting melanin synthesis. Additionally, it stimulates melanin production by regulating tryptophan metabolism. Compared to Ruxolitinib, PPL agonist-1 demonstrates superior effectiveness and holds potential for vitiligo research.

Microtubule Associated, Tyrosinase

Proteases/Proteasome, Cytoskeletal Signaling

3040936

C25H22FN5O4S

507.54

CC=1C=C(C2=CC=C([C@@H](NC=3N=C(NS(=O)(=O)C4=CC(N(=O)=O)=CC=C4)C=CN3)C)C=C2)C=CC1F

-20°C

Ice Packs

Small Compound