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PQCA - CAS 1144504-35-7
PQCA - CAS 1144504-35-7
SKU:MF-0024718-01
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$45.13 USD
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Product Details
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Bioactivity
PQCA is a muscarinic M1 receptor-positive allosteric regulator, which is highly selective and effective. PQCA exhibited EC50 values of 49 nM in rhesus monkey and 135 nM in human M1 receptors, but showed no activity against other muscarinic receptors. PQCA is a potential compound for reducing cognitive deficits associated with Alzheimer's disease.
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Target
AChR
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Related Pathways
Neuroscience
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CAS Number
1144462
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Purity
0.9988
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Molecular Formula
C22H20N4O3
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Molecular Weight
388.42
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SMILES
OC(=O)c1cc(CN2CCC(CC2)(C#N)c2ccccn2)c2ccccn2c1=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound