Molfinity

PQR530 - CAS 1927857-61-1

SKU:MF-0014519-01

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Size 1 mg 5 mg 1 mL - 10 mM (in DMSO) 10 mg 25 mg 50 mg 100 mg

Product Details

Bioactivity
PQR530 is a highly potent dual pan-PI3K/mTORC1/2 inhibitor. PQR530 inhibited protein kinase B (PKB, pSer473) and ribosomal protein S6 (pS6, pSer235/236) phosphorylation with IC50 values of 0.07 μM. It also showing antitumor activity.
Target
MTOR, PI3K
Related Pathways
PI3K/Akt/mTOR signaling
CAS Number
1927795
Purity
0.9978
Molecular Formula
C18H23F2N7O2
Molecular Weight
407.42
SMILES
C[C@H]1COCCN1c1nc(nc(n1)-c1cnc(N)cc1C(F)F)N1CCOCC1
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound