PqsR-IN-3 - CAS 3033007-79-0

PqsR-IN-3 (compound 16e) is a selective inhibitor of the pqs system (IC50=3.7 μM) and its associated virulence factor pyocyanin (IC50=2.7 μM) . This compound inhibits the synthesis of bacterial biofilms and is significantly cytotoxic to Pseudomonas aeruginosa. Additionally, PqsR-IN-3 exhibits synergistic effects with various antibiotics, such as Ciprofloxacin and Tobramycin.

Antibacterial

Microbiology/Virology

3032928

C23H23N5O3

417.46

O=C1C=C(N(C(=C1O)CNCC=2N=NN(C2)C3=CC=C(OC=4C=CC=CC4)C=C3)C)C

-20°C

Ice Packs

Small Compound