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Molfinity

PR-924 - CAS 1416709-79-9

PR-924 - CAS 1416709-79-9

MF-0019981-01

$683.55 USD
$683.55 USD
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Product Details

  • Bioactivity

    PR-924 is a selective inhibitor of tripeptide epoxyketone immunoproteasome subunit LMP-7 (IC50: 22 nM) . PR-924 inhibits growth and triggers apoptosis in multiple myeloma (MM) cells. PR-924 has antitumor activities. PR-924 covalently modifies proteasomal N-terminal threonine active sites.

  • Target

    Proteasome, Apoptosis

  • Related Pathways

    Ubiquitination, Proteases/Proteasome, Apoptosis

  • CAS Number

    1416621

  • Molecular Formula

    C37H38N4O5

  • Molecular Weight

    618.72

  • SMILES

    C[C@@H](NC(=O)C1=C(C)c2ccccc2C1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound