(-) -Praeruptorin A - CAS 14017-71-1

(-) -Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis; it also can significantly suppress airway inflammation and airway remodeling induced by ovalbumin challenge, and is a potential candidate for the treatment of asthma. (-) -Praeruptorin A resensitizes Pgp-mediated MDR (Pgp-MDR) cancer cells to cancer drugs.

ATPase, Calcium Channel, IL Receptor, P-gp

Membrane transporter/Ion channel, Neuroscience, Immunology/Inflammation, Metabolism

13945

C21H22O7

386.4

C\C=C(\C)C(=O)O[C@@H]1[C@H](OC(C)=O)c2c(OC1(C)C)ccc1ccc(=O)oc21

-20°C

Ice Packs

Natural Product