Pralnacasan - CAS 192755-52-5

Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ. Pralnacasan is an effective, non-peptide, and orally active interleukin-1β converting enzyme inhibitor (Ki: 1.4 nM) . Pralnacasan has the potential for osteoarthritis and rheumatoid arthritis treatment.

Caspase, Others

Others, Proteases/Proteasome, Apoptosis

192698

C26H29N5O7

523.54

CCO[C@@H]1OC(=O)C[C@@H]1NC(=O)[C@@H]1CCCN2N1C(=O)[C@H](CCC2=O)NC(=O)c1nccc2ccccc12

-20°C

Ice Packs

Small Compound