Praziquantel - CAS 55268-74-1

Praziquantel (Droncit) increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculature through a subsequent increase in levels of calcium in the sarcoplasmic reticulum. Praziquantel is a pyrazinoisoquinoline derivative with anthelminthic property. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads to antigen exposure and elicit host defense responses to the worm.

Parasite, Calcium Channel, Antibiotic

Membrane transporter/Ion channel, Metabolism, Microbiology/Virology

55193

0.9986

C19H24N2O2

312.41

O=C(C1CCCCC1)N1CC2N(CCC3=C2C=CC=C3)C(=O)C1

-20°C

Ice Packs

Small Compound