Prexasertib - CAS 1234015-52-1

Prexasertib (LY2606368) is a selective checkpoint kinase 1 (CHK1) inhibitor (Ki 0.9 nM, IC50<1 nM) . Prexasertib causes double-stranded DNA breaks and replication mutations, leading to apoptosis. Prexasertib has antitumor activity.

Apoptosis, Chk

Apoptosis, Cell Cycle/Checkpoint

1234015-52-1

>99.99%

C18H19N7O2

365.39

COc1cccc(OCCCN)c1-c1cc(Nc2cnc(cn2)C#N)n[nH]1

-20°C

Ice Packs

Small Compound