Prexasertib Mesylate Hydrate - CAS 1234015-57-6

Prexasertib Mesylate Hydrate (LY2606368 Mesylate Hydrate) is an ATP-competitive, selective, second-generation cell cycle checkpoint kinase 1 (CHK1) inhibitor (IC50<1 nM, Ki: 0.9 nM) . It inhibits CHK2 (IC50: 8 nM) and RSK1 (IC50: 9 nM), induces double-stranded DNA breaks and replication mutations, triggers apoptosis, and exhibits potent anti-tumor effects.

Apoptosis, Chk, Others

Apoptosis, Cell Cycle/Checkpoint, Others

1233952

C19H25N7O6S

479.51

O.CS(O)(=O)=O.COc1cccc(OCCCN)c1-c1cc(Nc2cnc(cn2)C#N)n[nH]1

-20°C

Ice Packs

Small Compound