PRMT5-IN-47 - CAS 3065081-87-7

PRMT5-IN-47 (compound 20) is a potent, selective, and orally active MTA co-operative PRMT5 inhibitor, with an IC50 value of 15 nM. It exhibits antiproliferative and anticancer activity.

Histone Methyltransferase

Chromatin/Epigenetic

3064987

C24H22FN5O2

431.462

C(N(C)[C@H]1CN(CC1)C2=CC=C(C#N)C=C2)(=O)C=3C=C4C5=C(C(N)=NC4=CC3F)COC5

-20°C

Ice Packs

Small Compound