PRMT5-IN-48 - CAS 2640287-77-8

PRMT5-IN-48 (compound D3) is an orally active PRMT5 inhibitor with an IC50 of 20.7 nM, displaying antitumor activity. It effectively suppresses the growth of various cancer cells, induces apoptosis, and causes cell cycle arrest at the G0/G1 phase. PRMT5-IN-48 is applicable for research in non-Hodgkin's lymphoma (NHL) .

Histone Methyltransferase

Chromatin/Epigenetic

2640202

C30H37N5O3

515.646

C([C@@H](CN1CC=2C(CC1)=CC=CC2)O)N3CC4(C=5C(C3=O)=CC(NC6CC7(C6)CN(C(C)=O)C7)=NC5)CC4

-20°C

Ice Packs

Small Compound