Pro-Dasatinib - CAS 2468065-01-0

Pro-Dasatinib (compound 2j) is an amino acid analogue of Dasatinib and serves as a potent Src/Abl kinase inhibitor. It exhibits antiproliferative activity against K652 leukemia cancer cells, with an IC50 of 0.21 nM.

Src, Bcr-Abl

Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Angiogenesis

2468065-01-0

C25H29ClN8O2S

541.07

N(C1=CC(N2CCN(C(=O)[C@@H]3CCCN3)CC2)=NC(C)=N1)C=4SC(C(NC5=C(C)C=CC=C5Cl)=O)=CN4

-20°C

Ice Packs

Small Compound