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Probucol dithiobisphenol - CAS 6386-58-9
Probucol dithiobisphenol - CAS 6386-58-9
SKU:MF-0113632-01
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Product Details
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Bioactivity
Probucoldithiobisphenol (DTBP) is a derivative of Probucol. It stimulates the production of heme oxygenase 1 (HO-1) and exhibits antioxidant properties. In the Apoe−/− mouse model, Probucol dithiobisphenol reduces aortic atherosclerotic lesions, and in a rabbit arterial injury model, it promotes arterial re-endothelialization and suppresses restenosis. This compound is orally active.
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Target
ROS
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Related Pathways
Immunology/Inflammation
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CAS Number
6319
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Molecular Formula
C28H42O2S2
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Molecular Weight
474.762
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SMILES
OC=1C(=CC(SSC=2C=C(C(O)=C(C2)C(C)(C)C)C(C)(C)C)=CC1C(C)(C)C)C(C)(C)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound