Progranulin modulator-1 - CAS 2641013-11-6

Progranulin Modulator-1 (Compound 60) is an orally active compound that promotes progranulin (PGRN) secretion. It enhances the ability of BV-2 cells to elevate PGRN levels, exhibits low cytotoxicity, and possesses an inhibitory effect on hERG. The EC50 for PGRN is 83 nM, and the IC50 for hERG is 3100 nM [1].

Others, TNF

Apoptosis, Others

2641013-11-6

C21H21F2N3O

369.41

FC1=CC=C([C@@H]2N(CCC=3C2=CC=CC3)C4=N[C@@H](CO4)[C@@]5(F)CNC5)C=C1

-20°C

Ice Packs

Small Compound