Molfinity

PROTAC AR/AR-V7 degrader-1 - CAS 2841308-96-9

SKU:MF-0121217-01

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Product Details

Bioactivity
PROTAC AR/AR-V7 degrader-1 (27c) serves as a dual degrader targeting both AR and AR-V7, showcasing DC50 values of 2.67 and 2.64 μM for AR and AR-V7, respectively. It effectively induces apoptosis.
Target
Apoptosis, PROTACs, Adrenergic Receptor
Related Pathways
Neuroscience, Apoptosis, GPCR/G Protein, PROTAC
CAS Number
2841308-96-9
Molecular Formula
C24H19F4N5O2
Molecular Weight
485.43
SMILES
O=C1N(C(=O)C(C)(C)N1CCNC=2C3=C(C(F)=CC2)N=CC=C3)C4=CC(C(F)(F)F)=C(C#N)C=C4
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
PROTAC