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PROTAC Bcl2 degrader-1 - CAS 2378801-85-3

PROTAC Bcl2 degrader-1 - CAS 2378801-85-3

MF-0004602-01

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Product Details

  • Bioactivity

    PROTAC Bcl2 degrader-1 is a PROTAC, which potently and selectively induces the degradation of Mcl-1 (IC50: 11.81 μM) and Bcl-2 (IC50: 4.94 μM; DC50: 3.0 μM) .

  • Target

    Bcl-2 Family, PROTACs

  • Related Pathways

    PROTAC, Apoptosis

  • CAS Number

    2378713

  • Molecular Formula

    C45H45BrN6O10S

  • Molecular Weight

    941.84

  • SMILES

    O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCOCCOCCNC(=O)CCCCC(=O)NCCN4C(=O)C5=CC=CC=6C(SC7=CC=C(Br)C=C7)=CC=C(C4=O)C56)C3C2=O)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC