PROTAC BET Degrader-10 - CAS 1957234-97-7

PROTAC BET Degrader-10 (WO2017007612A1, example 37) is a highly efficient and selective small molecule compound designed to degrade BET protein BRD4. PROTAC BET Degrader-10 functions by utilizing specific ligands that connect Cereblon and BRD4, with a DC 50 value of 49 nM.

Epigenetic Reader Domain, PROTACs

PROTAC, Chromatin/Epigenetic

1957130

C39H39ClN8O6S

783.3

Cc1nnc2[C@H](CC(=O)NCCCCCC(=O)NCc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |c:41|

-20°C

Ice Packs

PROTAC