PROTAC BRD4 Degrader-21 - CAS 2503036-46-0

PROTAC BRD4 Degrader-21 (Comp 74), a potent BRD4 degrader, has shown significant inhibition of tumor growth in mouse xenograft models, indicating its potential for anticancer research [1].

PROTACs, Epigenetic Reader Domain

Chromatin/Epigenetic, PROTAC

2502990

C47H54Cl2N10O4S

925.97

CC=1C2=C(N3C([C@H](CC(=O)N4CCC(CN5CCN(CC6=CC=C(C=C6)N7C(=NNC7=O)C8=CC(C(C)C)=C(O)C=C8O)CC5)CC4)N=C2C9=CC=C(Cl)C=C9)=NN=C3C)SC1C.Cl

-20°C

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PROTAC