PROTAC BRD4 Degrader-27 - CAS 2407163-44-2

PROTAC BRD4 Degrader-27 is a selective PROTAC targeting BRD4, distinguished from BRD2/BRD3. This compound is composed of the E3 ubiquitinase ligand Thalidomide-4-OH, the PROTAC Linker γ-Aminobutyric acid, and the PROTAC target protein ligand PROTAC BRD4 ligand-3. The active control for this target protein ligand is Mivebresib, while the conjugate of the E3 ubiquitin ligase ligand and Linker is identified as Pomalidomide 4'-alkylC3-acid.

PROTACs, Epigenetic Reader Domain

Chromatin/Epigenetic, PROTAC

2407163-44-2

C37H30F2N6O7

708.67

O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCCC(=O)NC=4C=CC(OC5=CC=C(F)C=C5F)=C(C4)C6=CN(C(=O)C=7NC=CC67)C)C3C2=O)CC1

-20°C

Ice Packs

PROTAC