PROTAC BTK Degrader-10 - CAS 2988804-46-0

PROTAC BTK Degrader-10 (Example 1P) is a PROTAC compound that targets BTK for degradation. It is applicable in the research of chronic lymphocytic leukemia (CLL) . [Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligase Cereblon].

PROTACs, BTK

Angiogenesis, PROTAC, Tyrosine Kinase/Adaptors

2988758

C42H49N11O4

771.91

N(C1=CC(=NC=N1)C2=CC(C)=C([C@H](NC(=O)C3=NC(C(C)(C)C)=NO3)C)C=C2)C4=CC=C(C=N4)N5[C@@H](C)CN(CCC6=CC=C(C=C6)N7C(=O)NC(=O)CC7)CC5

-20°C

Ice Packs

PROTAC