PROTAC BTK Degrader-6 - CAS 2767204-39-5

PROTAC BTK Degrader-6 (Compound 15), with a DC50 of 3.18 nM, exhibits anti-inflammatory properties by inhibiting NF-κB activation and suppressing the expression of pro-inflammatory cytokines such as IL-1β and IL-6 [1].

PROTACs, BTK

Angiogenesis, PROTAC, Tyrosine Kinase/Adaptors

2767160

C45H47N11O6

837.92

NC1=C2C(=NN(C2=NC=N1)C3CCN(C(CN4CCN(CC5CN(C5)C=6C=C7C(=CC6)C(=O)N(C7=O)C8C(=O)NC(=O)CC8)CC4)=O)CC3)C9=CC=C(OC%10=CC=CC=C%10)C=C9

-20°C

Ice Packs

PROTAC