PROTAC CDK9 degrader-6 - CAS 2935587-91-8

PROTAC CDK9 degrader-6 is a specific PROTAC targeting CDK9 for degradation via the proteasome pathway, effectively degrading CDK9 with DC50 values of 0.10 μM and 0.14 μM for the CDK9 42 and CDK9 55 isoforms, respectively [1].

CDK

Cell Cycle/Checkpoint

2935488

C42H49Cl2N9O8

878.8

O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCC(NCCCCCCCCCCC(=O)N4CCC(NC(=O)C=5C(NC(=O)C6=C(Cl)C=CC=C6Cl)=CNN5)CC4)=O

-20°C

Ice Packs

PROTAC