PROTAC ERα Degrader-8 - CAS 3025533-68-7

PROTAC ERα Degrader-8 (compound ii-56), a highly potent degrader of Erα, achieves a DC50 of just 0.000006 μM in MCF7 cells [1].

PROTACs, Estrogen Receptor/ERR

PROTAC, Endocrinology/Hormones

3025533-68-7

C47H51N5O4

749.94

OC=1C=C2C([C@@H]([C@@H](CC2)C3=CC=CC=C3)C4=CC=C(C=C4)N5C6(CC(CN7CCN(CC7)C=8C=C9C(=CC8)C(=O)N(C9)[C@@H]%10C(=O)NC(=O)CC%10)CC5(CC6)[H])[H])=CC1

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PROTAC