PROTAC ERK5 degrader-1 - CAS 2919963-24-7

PROTACERK5 degrader-1 (compound 2) is a bifunctional ERK5 PROTAC degrader. It induces the degradation of ERK5 in MOLT-4 cells via a VHL-mediated proteasome pathway. PROTACERK5 degrader-1 is useful for studying diseases or disorders characterized by abnormal ERK5 activity.

PROTACs, ERK

PROTAC, MAPK

2919932

C54H67F3N10O6S

1041.23

C(=O)(N1CCC(C=2C3=C(C=C(C=C3)N4CCN(CCCCCC(N[C@H](C(=O)N5[C@H](C(N[C@@H](C)C6=CC=C(C=C6)C7=C(C)N=CS7)=O)C[C@@H](O)C5)C(C)(C)C)=O)CC4)N=CN2)CC1)C8=C(N)C=C(OC(F)(F)F)C=C8

-20°C

Ice Packs

PROTAC