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PROTAC GSPT1 degrader-2 - CAS 3024909-61-0

PROTAC GSPT1 degrader-2 - CAS 3024909-61-0

MF-0121946-01

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Product Details

  • Bioactivity

    PROTACGSPT1 degrader-2 (compound A) acts as a molecular glue for GSPT1, achieving degradation efficiencies exceeding 95%. Meanwhile, GSPT1 degrader-8 exhibits inhibitory effects on HL-60 cells, demonstrating an IC50 of 10 nM.

  • CAS Number

    3024909-61-0

  • Molecular Formula

    C38H38ClN7O5

  • Molecular Weight

    708.21

  • SMILES

    O=C1NC(=O)C(N2C(=O)C3=CC=C(C=C3C2=O)N4CCC(CN5C(=O)N(C=6C=CC=C(C6)C=7C=NC=8NC=C(C8C7Cl)CC)CCC5)CC4)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC