PROTAC HDAC6 degrader 1 - CAS 2785404-76-2

Compound A6, a potent and selective PROTAC HDAC6 degrader, exhibits a DC50 of 3.5 nM. It demonstrates notable antiproliferative activity by inducing apoptosis in myeloid leukemia cell lines [1].

HDAC, Others, Apoptosis, PROTACs

Apoptosis, Others, DNA Damage/DNA Repair, Chromatin/Epigenetic, PROTAC

2785326

C37H46N6O10

734.8

O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2OCC(NCCCCCCCC(NC4=CC=C(C(NCCCCCCC(NO)=O)=O)C=C4)=O)=O

-20°C

Ice Packs

PROTAC