PROTAC IRAK3 degrade-1 - CAS 2712600-00-3

PROTAC IRAK3 degrade-1 is a potent and selective degrader of IRAK3 (IC 50 = 5 nM) .

Others, PROTACs

Others, PROTAC

2712600-00-3

C47H63N11O6

878.092

CC(C)c1ccn2ncnc(N[C@H]3CC[C@H](CC3)N3CCN(CC3)C(=O)CCC(=O)N3CCC(CCN4CCN(CC4)c4ccc5C(=O)N(C6CCC(=O)NC6=O)C(=O)c5c4)CC3)c12 |wU:15.18,12.11,(-.91,-3.09,;-1.94,-1.94,;-3.45,-2.26,;-1.46,-.48,;-2.37,.77,;-1.46,2.02,;,1.54,;1.33,2.31,;2.67,1.54,;2.67,,;1.33,-.77,;1.33,-2.31,;2.67,-3.08,;4,-2.31,;5.33,-3.08,;5.33,-4.62,;4,-5.39,;2.67,-4.62,;6.67,-5.39,;6.67,-6.93,;8,-7.7,;9.34,-6.93,;9.34,-5.39,;8,-4.62,;10.67,-7.7,;10.67,-9.24,;12,-6.93,;13.34,-7.7,;14.67,-6.93,;14.67,-5.39,;16,-7.7,;16,-9.24,;17.34,-10.01,;18.67,-9.24,;20.01,-10.01,;21.34,-9.24,;22.67,-10.01,;22.67,-11.55,;24.01,-12.32,;25.34,-11.55,;25.34,-10.01,;24.01,-9.24,;26.67,-12.32,;26.67,-13.86,;28.01,-14.63,;29.34,-13.86,;30.81,-14.34,;31.28,-15.8,;31.71,-13.09,;33.25,-13.09,;34.02,-14.42,;35.56,-14.42,;36.33,-13.09,;37.87,-13.09,;35.56,-11.76,;34.02,-11.76,;33.25,-10.42,;30.81,-11.84,;31.28,-10.38,;29.34,-12.32,;28.01,-11.55,;18.67,-7.7,;17.34,-6.93,;)|

-20°C

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